Nicole M Iovine

Nicole M Iovine, MD, PhD

Program Director; Clinical Professor & Hospital Epidemiologist

Department: MD-INFECTIOUS DISEASES
Business Phone: (352) 273-8606

Accomplishments

Excellence in Teaching Award
2012 · University of Florida
Special Citation of Excellence for a Poster Presentation
2005 · 43rd Annual Meeting of the IDSA
Infectious Disease Fellow of the Year
2002 · unknown

Board Certifications

  • Infectious Disease
    American Board of Internal Medicine
  • Internal Medicine
    American Board of Internal Medicine

Clinical Profile

Specialties
  • Medicine
Subspecialties
  • Infectious Disease
Areas of Interest
  • Haemophilus influenzae┬áType b (Hib) vaccine – what you need to know
  • Infectious diseases

Publications

2021
Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19.
The New England journal of medicine. 384(9):795-807 [DOI] 10.1056/NEJMoa2031994. [PMID] 33306283.
2021
Dissemination mechanisms of NDM genes in hospitalized patients.
JAC-antimicrobial resistance. 3(1) [DOI] 10.1093/jacamr/dlab032. [PMID] 34223104.
2020
Evaluation of patient risk factors for infection with carbapenem-resistant Enterobacteriaceae.
American journal of infection control. 48(9):1028-1031 [DOI] 10.1016/j.ajic.2019.11.025. [PMID] 31924388.
2020
Optimizing COVID-19 testing capabilities and clinical management using pathology informatics.
JAMIA open. 3(4):523-529 [DOI] 10.1093/jamiaopen/ooaa055. [PMID] 33754137.
2020
Recovery of Curvularia mold from a duodenoscope after reprocessing in accordance with the manufacturer’s cleaning protocol.
American journal of infection control. 48(1):119-121 [DOI] 10.1016/j.ajic.2019.06.025. [PMID] 31439371.
2020
The Clinical Presentation and Immunology of Viral Pneumonia and Implications for Management of Coronavirus Disease 2019.
Critical care explorations. 2(4) [DOI] 10.1097/CCE.0000000000000109. [PMID] 32426751.
2018
IKBKG (NEMO) 5′ Untranslated Splice Mutations Lead to Severe, Chronic Disseminated Mycobacterial Infections.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 67(3):456-459 [DOI] 10.1093/cid/ciy186. [PMID] 29534156.
2018
Infectious Diseases Physicians: Leading the Way in Antimicrobial Stewardship.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 66(7):995-1003 [DOI] 10.1093/cid/cix1093. [PMID] 29444247.
2017
Complete Genome Sequence of Dengue virus Type 2 from a Resident of North-Central Florida with Locally Transmitted Dengue Fever.
Genome announcements. 5(31) [DOI] 10.1128/genomeA.00782-17. [PMID] 28774993.
2016
Hemagglutinin Gene Clade 3C.2a Influenza A(H3N2) Viruses, Alachua County, Florida, USA, 2014-15.
Emerging infectious diseases. 22(1):121-3 [DOI] 10.3201/2201.151019. [PMID] 26692074.
2016
Zika and Chikungunya virus co-infection in a traveller returning from Colombia, 2016: virus isolation and genetic analysis.
JMM case reports. 3(6) [DOI] 10.1099/jmmcr.0.005072. [PMID] 28348794.
2015
An outbreak of acute delirium from exposure to the synthetic cannabinoid AB-CHMINACA.
Clinical toxicology (Philadelphia, Pa.). 53(10):950-6 [DOI] 10.3109/15563650.2015.1100306. [PMID] 26555732.
2015
Effects of Klebsiella pneumoniae carbapenemase subtypes, extended-spectrum ╬▓-lactamases, and porin mutations on the in vitro activity of ceftazidime-avibactam against carbapenem-resistant K. pneumoniae.
Antimicrobial agents and chemotherapy. 59(9):5793-7 [DOI] 10.1128/AAC.00548-15. [PMID] 26169413.
2015
Severity of influenza A(H1N1) illness and emergence of D225G variant, 2013-14 influenza season, Florida, USA.
Emerging infectious diseases. 21(4):664-7 [DOI] 10.3201/eid2104.141375. [PMID] 25811540.
2014
Carbapenem-resistant Klebsiella pneumoniae strains exhibit diversity in aminoglycoside-modifying enzymes, which exert differing effects on plazomicin and other agents.
Antimicrobial agents and chemotherapy. 58(8):4443-51 [DOI] 10.1128/AAC.00099-14. [PMID] 24867988.
2014
Detection of Neisseria meningitidis from negative blood cultures and cerebrospinal fluid with the FilmArray blood culture identification panel.
Journal of clinical microbiology. 52(6):2262-4 [DOI] 10.1128/JCM.00352-14. [PMID] 24740076.
2014
Enteric bacteria promote human and mouse norovirus infection of B cells.
Science (New York, N.Y.). 346(6210):755-9 [DOI] 10.1126/science.1257147. [PMID] 25378626.
2014
High Percentage of False-Positive Results for Influenza B Obtained With a Rapid Influenza Point-Of-Care Test
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 59(4):605+-5 [DOI] 10.1093/cid/ciu315. [PMID] 24795330.
2013
Log reduction of multidrug-resistant Gram-negative bacteria by the neutrophil-derived recombinant bactericidal/permeability-increasing protein.
International journal of antimicrobial agents. 42(6):571-4 [DOI] 10.1016/j.ijantimicag.2013.07.019. [PMID] 24189329.
2013
Multi-functional analysis of Klebsiella pneumoniae fimbrial types in adherence and biofilm formation.
Virulence. 4(2):129-38 [DOI] 10.4161/viru.22974. [PMID] 23302788.
2013
Resistance mechanisms in Campylobacter jejuni.
Virulence. 4(3):230-40 [DOI] 10.4161/viru.23753. [PMID] 23406779.
2012
Antibacterial analysis of surgical adhesives.
Plastic and reconstructive surgery. 129(2):402e-404e [DOI] 10.1097/PRS.0b013e31823af194. [PMID] 22286489.
2011
Campylobacter capsule and lipooligosaccharide confer resistance to serum and cationic antimicrobials.
Virulence. 2(1):30-40 [PMID] 21266840.
View on: PubMed
2008
Reactive nitrogen species contribute to innate host defense against Campylobacter jejuni.
Infection and immunity. 76(3):986-93 [DOI] 10.1128/IAI.01063-07. [PMID] 18174337.
2006
A paradigm for direct stress-induced mutation in prokaryotes.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 20(14):2476-85 [PMID] 17142797.
View on: PubMed
2004
Antibiotics in animal feed and spread of resistant Campylobacter from poultry to humans.
Emerging infectious diseases. 10(6):1158-9 [PMID] 15224671.
View on: PubMed
2004
Antimicrobial resistance in Campylobacter.
Emerging infectious diseases. 10(7) [PMID] 15338553.
View on: PubMed
2002
The carboxyl-terminal domain of closely related endotoxin-binding proteins determines the target of protein-lipopolysaccharide complexes.
The Journal of biological chemistry. 277(10):7970-8 [PMID] 11773072.
View on: PubMed
1997
An opsonic function of the neutrophil bactericidal/permeability-increasing protein depends on both its N- and C-terminal domains.
Proceedings of the National Academy of Sciences of the United States of America. 94(20):10973-8 [PMID] 9380744.
View on: PubMed
1997
Lipopolysaccharide (LPS)-binding proteins BPI and LBP form different types of complexes with LPS.
The Journal of biological chemistry. 272(30):18682-5 [PMID] 9228038.
View on: PubMed

Grants

May 2021 ACTIVE
Prevalence of Cefazolin Inoculum Effect in Mcthicillin Susceptible Staphylococcus aureus Bacteremia
Role: Co-Investigator
Funding: UF HEALTH SHANDS HOSPITAL
Oct 2020 ACTIVE
COVID-19: A Multicenter, Adaptive, Randomized Controlled Platform Trial of the Safety and Efficacy of Antithrombotic Strategies in Hospitals Adults with COVID-19
Role: Principal Investigator
Funding: NEW YORK UNIV via NATL INST OF HLTH NHLBI
Mar 2020 – Aug 2021
A Multicenter, Adaptive, Randomized Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for the Treatment of COVID-19 in Hospitalized Adults
Role: Principal Investigator
Funding: LEIDOS via NATL INST OF HLTH NIAID
Sep 2016 – May 2018
Mucusal and Systemic Immunity, Vaccines and Microbiota Interplay in Humans
Role: Principal Investigator
Funding: UNIV OF MARYLAND COLLEGE PARK via NATL INST OF HLTH NIAID

Education

Fellowship – Infectious Disease
2005 · New York University
Residency – Internal Medicine
2002 · New York University
Internship – Internal Medicine
2001 · New York University
Medical Degree
2000 · New York University
Bachelor of Arts – Biology
1992 · City University of New York

Teaching Profile

Courses Taught
2018
MDT7200 Elect Top/Medicine
2018
BMS6300 Fund Micro and Immuno

Contact Details

Phones:
Business:
(352) 273-8606
Emails: